TTD | Drug: D04BXL

Drug General Information
Drug ID	D04BXL
Former ID	DNC006238
Drug Name	2-morpholino-7-(2-phenylethynyl)-4H-chromen-4-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527870]
Structure		Download 2D MOL 3D MOL
Formula	C21H17NO3
Canonical SMILES	C1COCCN1C2=CC(=O)C3=C(O2)C=C(C=C3)C#CC4=CC=CC=C4
InChI	1S/C21H17NO3/c23-19-15-21(22-10-12-24-13-11-22)25-20-14-17(8-9-18(19)20)7-6-16-4-2-1-3-5-16/h1-5,8-9,14-15H,10-13H2
InChIKey	INSPUQMNGZSNFZ-UHFFFAOYSA-N
PubChem Compound ID	44328640
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[527870]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
Reactome	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
WikiPathways	miR-targeted genes in lymphocytes - TarBase
References
Ref 527870	Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.
Ref 527870	Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.

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Drug Information