Drug Information

Drug General Information
Drug ID
D04INP
Former ID
DIB004920
Drug Name
Pixykine
Synonyms
Milodistim; Plasmid Immunex yeast 321; PIXY-321
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Phase 3 [521422]
Company
Immunex Corp
CAS Number
CAS 137463-76-4
Target and Pathway
Target(s) Granulocyte-macrophage colony-stimulating factor receptor alpha chain Target Info Modulator
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Hematopoietic cell lineage
Pathways in cancer
NetPath Pathway IL3 Signaling Pathway
RANKL Signaling Pathway
Pathway Interaction Database GMCSF-mediated signaling events
Alpha9 beta1 integrin signaling events
Reactome GPVI-mediated activation cascade
G beta:gamma signalling through PI3Kgamma
Interleukin-3, 5 and GM-CSF signaling
RAF/MAP kinase cascade
Surfactant metabolism
Interleukin receptor SHC signaling
WikiPathways Interleukin-2 signaling
Interleukin-3, 5 and GM-CSF signaling
References
Ref 521422ClinicalTrials.gov (NCT00001338) A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer. U.S. National Institutes of Health.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.