Drug General Information
Drug ID	D04JSS
Drug Name	MK-771
Synonyms	66537-55-1; MK-771
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1560060]
Structure		Download 2D MOL 3D MOL
Formula	C16H22N6O4S
PubChem Compound ID	163122
Target and Pathway
Target(s)	Thyrotropin-releasing hormone receptor	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
PANTHER Pathway	Thyrotropin-releasing hormone receptor signaling pathway
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 1560060	TRH analog MK-771 reverses neurochemical and learning deficits in medial septal-lesioned rats.

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