Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04JWS
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| Former ID |
DNC007823
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| Drug Name |
NSC-292213
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [529029] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C24H14O8
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=CC(=C2O)C(=O)O)C(=O)C(=O)C3=CC(=C(C4=C<br />C=CC=C43)O)C(=O)O
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| InChI |
1S/C24H14O8/c25-19-13-7-3-1-5-11(13)15(9-17(19)23(29)30)21(27)22(28)16-10-18(24(31)32)20(26)14-8-4-2-6-12(14)16/h1-10,25-26H,(H,29,30)(H,31,32)
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| InChIKey |
BRCWHTNRFUVIQT-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 12-lipoxygenase, 12S-type | Target Info | Inhibitor | [529029] | |
| Phosphoribosylaminoimidazolecarboxamide formyltransferase | Target Info | Inhibitor | [527350] | ||
| BioCyc Pathway | Lipoxin biosynthesis | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | |||||
| References | |||||
| Ref 527350 | J Med Chem. 2004 Dec 30;47(27):6681-90.Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors. | ||||
| Ref 529029 | Bioorg Med Chem. 2007 Nov 15;15(22):6900-8. Epub 2007 Aug 22.Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries. | ||||
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