Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04KYY
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| Former ID |
DAP000773
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| Drug Name |
Allopurinol
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| Synonyms |
Adenock; Ailural; Ailurial; Allohexal; Allohexan; Alloprin; Allopur; Allopurin; Allopurinolum; Allorin; Allozym; Allpargin; Allural; Aloprim; Alopurinol; Aloral; Alositol; Aluline; Anoprolin; Anzief; Apulonga; Apurin; Apurol; Atisuril; Bleminol; Bloxanth; Caplenal; Capurate; Cellidrin; Cosuric; Dabrosin; Dabroson; Embarin; Epidropal; Epuric; Foligan; Geapur; Gichtex; Gotax; Hamarin; Hexanuret; Jenapurinol; Ketanrift; Ledopur; Lopurin; Lysuron; Milurit; Milurite; Miniplanor; Monarch; Nektrohan; Novopurol; Progout; Pureduct; Purinol; Remid; Riball; Rimapurinol; Roucol; Sigapurol; Suspendol; Takanarumin; Tipuric; Urbol; Uribenz; Uricemil; Uridocid; Uriprim; Uripurinol; Uritas; Urobenyl; Urolit; Urosin; Urtias; Xanthomax; Xanturat; Xanturic; Zygout; Zyloprim; Zyloric; Dura Al; Pan Quimica; A 8003; BW 56158; Urtias 100; AL-100; Allo-Puren; Allohexal (TN); Allopurinol(I); Allosig (TN); Apo-Allopurinol; BW 56-158; Ketobun-A; Progout (TN); Puricos (TN); Quimica, Pan; Zyloprim (TN); Zyloric (TN); BW-56-158; B. W. 56-158; 4-HPP
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antimetabolites
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| Company |
GlaxoSmithKline
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| Structure |
|
Download2D MOL |
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| Formula |
C5H4N4O
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| InChI |
InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
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| InChIKey |
OFCNXPDARWKPPY-UHFFFAOYSA-N
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| CAS Number |
CAS 315-30-0
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| PubChem Compound ID | |||||
| PubChem Substance ID |
68199, 404525, 594917, 3133506, 3727085, 4266415, 4826301, 6262863, 7348782, 7836064, 8139898, 8149190, 10321496, 10518263, 11110781, 11335860, 11361099, 11362800, 11365362, 11367924, 11371398, 11373689, 11376086, 11449337, 11462071, 11483792, 11487914, 11490105, 11491950, 11493840, 15119988, 15146664, 17389550, 17404665, 22395219, 24278141, 26611594, 26679243, 26697339, 26747845, 26747846, 29221274, 42880554, 46508516, 47440268, 47589009, 47737041, 48259236, 48415533, 48422551
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| ChEBI ID |
ChEBI:40279
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| SuperDrug ATC ID |
M04AA01
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| SuperDrug CAS ID |
cas=000315300
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| Target and Pathway | |||||
| Target(s) | Xanthine dehydrogenase/oxidase | Target Info | Inhibitor | [535076], [537771], [538067] | |
| PANTHER Pathway | Adenine and hypoxanthine salvage pathway | ||||
| Purine metabolism | |||||
| PathWhiz Pathway | Caffeine Metabolism | ||||
| Purine Metabolism | |||||
| Reactome | Purine catabolism | ||||
| References | |||||
| Ref 538511 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018659. | ||||
| Ref 541876 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6795). | ||||
| Ref 535076 | Purification, crystallization and preliminary X-ray diffraction studies of xanthine dehydrogenase and xanthine oxidase isolated from bovine milk. Acta Crystallogr D Biol Crystallogr. 2000 Dec;56(Pt 12):1656-8. | ||||
| Ref 537771 | Allopurinol: xanthine oxidase inhibitor. Tex Med. 1966 Jan;62(1):100-1. | ||||
| Ref 538067 | Influence of postischemic administration of oxyradical antagonists on ischemic injury to rabbit skeletal muscle. Microsurgery. 1996;17(9):517-23. | ||||
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