Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04NJS
|
||||
| Former ID |
DCL000637
|
||||
| Drug Name |
SAR351034
|
||||
| Indication | Type 2 diabetes; Dyslipidemia [ICD9: 250, 250.00, 250.02, 272; ICD10:E08-E13, E11, E78] | Phase 1 | [1] | ||
| Company |
Sanofi-Aventis
|
||||
| Target and Pathway | |||||
| Target(s) | Peroxisomeproliferator activated receptor delta | Target Info | Modulator | [2] | |
| KEGG Pathway | PPAR signaling pathway | ||||
| Wnt signaling pathway | |||||
| Pathways in cancer | |||||
| Acute myeloid leukemia | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Wnt signaling pathway | ||||
| Pathway Interaction Database | Presenilin action in Notch and Wnt signaling | ||||
| RXR and RAR heterodimerization with other nuclear receptor | |||||
| Reactome | Import of palmitoyl-CoA into the mitochondrial matrix | ||||
| Regulation of pyruvate dehydrogenase (PDH) complex | |||||
| Nuclear Receptor transcription pathway | |||||
| WikiPathways | Wnt Signaling Pathway and Pluripotency | ||||
| Nuclear Receptors in Lipid Metabolism and Toxicity | |||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| Vitamin D Receptor Pathway | |||||
| Ectoderm Differentiation | |||||
| Adipogenesis | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029833) | ||||
| REF 2 | Addressing Unmet Medical Needs in Type 2 Diabetes: A Narrative Review of Drugs under Development. Curr Diabetes Rev. 2015 March; 11(1): 17-31. | ||||
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