Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04PGO
|
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| Former ID |
DIB005787
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| Drug Name |
MDL-28133A
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| Drug Type |
Small molecular drug
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| Indication | Thromboembolism [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] | Terminated | [1] | ||
| Company |
Hoechst Marion Roussel Inc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C21H24ClFN2O4S
|
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| Canonical SMILES |
S(=O)(=O)(Nc1ccc(C(=O)C2CCN(CC(=O)c3ccc(cc3)F)CC2)cc1)C<br />.Cl
|
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| CAS Number |
CAS 136861-96-6
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-HT 2 receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002814) | ||||
| REF 2 | Effects of MDL 28,133A, a 5-HT2 receptor antagonist, on platelet aggregation and coronary thrombosis in dogs. J Cardiovasc Pharmacol. 1994 Nov;24(5):761-72. | ||||
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