Drug Information
Drug General Information | |||||
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Drug ID |
D04QUD
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Former ID |
DIB014354
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Drug Name |
PDE4 inhibitors
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Synonyms |
PDE4 inhibitors (oral, COPD); PDE4 inhibitors (oral, COPD), GlaxoSmithKline
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Indication | Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] | Investigative | [552138] | ||
Company |
GlaxoSmithKline plc
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Structure |
Download2D MOL |
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Canonical SMILES |
c1(cnc2c(c1Nc1ccc(c(c1)OC)F)cc(cc2C)S(=O)(=O)C)C(=O)N
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Target and Pathway | |||||
Target(s) | CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [543404] | |
CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [543405] | ||
Type IV phosphodiesterase | Target Info | Inhibitor | [543406] | ||
NetPath Pathway | IL5 Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
PathWhiz Pathway | Purine Metabolism | ||||
References | |||||
Ref 543404 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1300). | ||||
Ref 543405 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1301). | ||||
Ref 543406 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1303). |
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