Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04QZI
|
||||
| Former ID |
DNCL003578
|
||||
| Drug Name |
Retosiban
|
||||
| Drug Type |
Small molecular drug
|
||||
| Company |
GlaxoSmithKline
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C27H34N4O5
|
||||
| InChI |
InChI=1S/C27H34N4O5/c1-4-16(2)23-25(32)29-22(20-13-18-7-5-6-8-19(18)14-20)26(33)31(23)24(21-15-36-17(3)28-21)27(34)30-9-11-35-12-10-30/h5-8,15-16,20,22-24H,4,9-14H2,1-3H3,(H,29,32)/t16-,22+,23+,24+/m0/s1
|
||||
| InChIKey |
PLVGDGRBPMVYPB-FDUHJNRSSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Oxytocin receptor | Target Info | Modulator | ||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| PANTHER Pathway | Oxytocin receptor mediated signaling pathway | ||||
| References | |||||
| Ref 525102 | ClinicalTrials.gov (NCT02377466) A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor. U.S. National Institutes of Health. | ||||
| Ref 543110 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8403). | ||||
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