Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04RRZ
|
||||
| Former ID |
DNCL003372
|
||||
| Drug Name |
MEDI4736
|
||||
| Company |
AstraZeneca
|
||||
| Target and Pathway | |||||
| Target(s) | Programmed cell deathe?Y? ligand 1 (PD-L1) | Target Info | Modulator | [550491] | |
| KEGG Pathway | Cell adhesion molecules (CAMs) | ||||
| Reactome | PD-1 signaling | ||||
| WikiPathways | Costimulation by the CD28 family | ||||
| References | |||||
| Ref 524965 | ClinicalTrials.gov (NCT02273375) Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC. U.S. National Institutes of Health. | ||||
| Ref 542899 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7985). | ||||
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