Drug Information

Drug General Information
Drug ID
D04TLJ
Former ID
DIB010149
Drug Name
Soblidotin
Synonyms
Auristatin PE; Dolastatin derivative; TZT-1027; YHI-501; ZT-1027
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 2 [521565]
Company
Teikoku Hormone Manufacturing Co Ltd
Structure
Download
2D MOL

3D MOL
Formula
C39H67N5O6
Canonical SMILES
C(=O)(N([C@H]([C@@H](CC(=O)N1[C@H]([C@@H]([C@H](C(=O)NC<br />Cc2ccccc2)C)OC)CCC1)OC)[C@H](CC)C)C)[C@@H](NC(=O)[C@@H]<br />(N(C)C)C(C)C)C(C)C
CAS Number
CAS 149606-27-9
PubChem Compound ID
24978490
Target and Pathway
Target(s) Tubulin Target Info Modulator [528298]
References
Ref 521565ClinicalTrials.gov (NCT00064220) Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma. U.S. National Institutes of Health.
Ref 528298Antitumor activity of TZT-1027 (Soblidotin). Anticancer Res. 2006 May-Jun;26(3A):1973-81.

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