Drug Information

Drug General Information
Drug ID
D04TMQ
Former ID
DAP001468
Drug Name
D-cycloserine
Synonyms
Cicloserina; Closerin; Closina; Cyclorin; Cycloserine; Cycloserinum; Farmiserina; Micoserina; Miroserina; Miroseryn; Novoserin; Orientomycin; Oxamicina; Oxamycin; Seromycin; Tebemicina; Tisomycin; Wasserina; Cicloserina [Italian]; Oxamicina [Italian]; C 3909; PA 94; Alpha-Cycloserine; C-9390; C-9400; Cicloserina [INN-Spanish]; Cycloserinum [INN-Latin]; D-CS; DRG-0195; I-1431; K-300; PA-94; SC-49088; Seromycin (TN); Cyclo-D-serine; Cycloserine [INN:BAN:JAN]; E-733-A; RO-1-9213; Cycloserine (JP15/USP/INN); D-amino-3-isoxazolidinone; D-(+)-Cycloserine; D-4-Amino-3-isossazolidone; D-4-Amino-3-isossazolidone [Italian]; D-4-amino-3-isoxazolidinone; D-4-amino-3-isoxazolidone; FA6C7F8B-D080-4EA3-978F-1ECFB5A29D09; R-(+)-Cycloserine; R-4-Amino-3-isoxazolidinone; R(+)-4-Amino-3-isoxazolidinone; (+)-4-Amino-3-isoxazolidinone; (+)-Cycloserine; (4R)-4-Amino-3-isoxazolidinone; (4R)-4-amino-1,2-oxazolidin-3-one; (4R)-4-aminoisoxazolidin-3-one; (R)-(+)-4-Amino-3-isoxazolidinone; (R)-(+)-Cycloserine; (R)-4-AMINO-ISOXAZOLIDIN-3-ONE; (R)-4-Amino-3-isoxazolidinone; (R)-4-Amino-3-isoxazolidone; (R)-Cycloserine; 3-Isoxazolidinone, 4-amino-, (+)-(8CI); 3-Isoxazolidinone, 4-amino-, (4R)-(9CI); 3-Isoxazolidinone, 4-amino-, (R); 3-Isoxazolidinone, 4-amino-, D
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [536854]
Obsessive compulsive disorder [ICD9: 300.3; ICD10:F42] Phase 2 [536854]
Company
Eli Lilly
Structure
Download
2D MOL

3D MOL
Formula
C3H6N2O2
Canonical SMILES
C1C(C(=O)NO1)N
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChIKey
DYDCUQKUCUHJBH-UWTATZPHSA-N
CAS Number
CAS 68-41-7
PubChem Compound ID
6234
PubChem Substance ID
10257, 602895, 829389, 841629, 3139717, 7847941, 7885338, 7979010, 8149277, 8153915, 11110913, 11110914, 11110915, 11112194, 11112195, 11335273, 11360512, 11363754, 11366316, 11368878, 11371441, 11374029, 11377040, 11461484, 11467117, 11468237, 11483744, 11486765, 11487900, 11490187, 11492120, 11494674, 12014545, 15170469, 17404815, 24277962, 24858076, 24892907, 24892979, 25622405, 26611680, 26679210, 26719637, 29214856, 29225230, 46386864, 46392863, 46506865, 46507135, 47216632
ChEBI ID
ChEBI:40009
SuperDrug ATC ID
J04AB01
SuperDrug CAS ID
cas=000068417
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) NMDA receptor Target Info Agonist [536773], [536854]
References
Ref 536854Has nature already identified all useful antibacterial targets? Curr Opin Microbiol. 2008 Oct;11(5):387-92. Epub 2008 Oct 6.
Ref 536773How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30.
Ref 536854Has nature already identified all useful antibacterial targets? Curr Opin Microbiol. 2008 Oct;11(5):387-92. Epub 2008 Oct 6.

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