Drug Information

Drug General Information
Drug ID
D04TNR
Former ID
DNCL002781
Drug Name
Dronabinol oral solution
Indication Chemotherapy-induced nausea [ICD9: 787, 787.0; ICD10:R11] Phase 2/3 [551036]
Company
INSYS Therapeutics
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Modulator [1572591]
Cannabinoid receptor 1 Target Info Modulator [1572591]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 551036Clinical pipeline report, company report or official report of INSYS Therapeutics.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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