TTD | Drug: D04UNE

Drug General Information
Drug ID	D04UNE
Former ID	DIB020535
Drug Name	NIHP
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540851]
Structure		Download 2D MOL
Formula	C15H25NO3
InChI	InChI=1S/C15H25NO3/c1-12(2)16-10-14(18)11-19-15-7-5-13(6-8-15)4-3-9-17/h5-8,12,14,16-18H,3-4,9-11H2,1-2H3
InChIKey	RUZBBQNQBDCLPE-UHFFFAOYSA-N
PubChem Compound ID	10587912
PubChem Substance ID	15616710, 22893734, 41223067, 75077935, 135650718, 240116671
Target and Pathway
Target(s)	Beta-3 adrenergic receptor	Target Info	Antagonist	[525440]
KEGG Pathway	Calcium signaling pathway
	cGMP-PKG signaling pathway
	Neuroactive ligand-receptor interaction
	Endocytosis
	Salivary secretion
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	Beta3 adrenergic receptor signaling pathway
Reactome	Adrenoceptors
Reactome	G alpha (s) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540851	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 545).
Ref 525440	LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors. Eur J Pharmacol. 1999 Feb 19;367(2-3):431-5.

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Drug Information