Drug Information
Drug General Information | |||||
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Drug ID |
D04WQJ
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Former ID |
DIB013777
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Drug Name |
AMG-181
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Synonyms |
Inflammatory bowel disease therapeutics, Amgen
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Drug Type |
Antibody
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Indication | Crohn's disease [ICD9: 555; ICD10:K50] | Phase 2 | [524078] | ||
Company |
Amgen; astrazeneca
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Target and Pathway | |||||
Target(s) | Integrin beta-7 | Target Info | [532239] | ||
KEGG Pathway | PI3K-Akt signaling pathway | ||||
Focal adhesion | |||||
ECM-receptor interaction | |||||
Cell adhesion molecules (CAMs) | |||||
Intestinal immune network for IgA production | |||||
Regulation of actin cytoskeleton | |||||
Transcriptional misregulation in cancer | |||||
Hypertrophic cardiomyopathy (HCM) | |||||
Arrhythmogenic right ventricular cardiomyopathy (ARVC) | |||||
Dilated cardiomyopathy | |||||
NetPath Pathway | IL2 Signaling Pathway | ||||
Wnt Signaling Pathway | |||||
References |
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