Drug Information

Drug General Information
Drug ID
D04XIO
Former ID
DIB013859
Drug Name
Dutogliptin
Synonyms
Dutogliptin tartrate; PHX-1004; PHX-1149; PHX-1149T; DPP IV inhibitors (diabetes), Phenomix; DPP IV program (diabetes), Phenomix
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 3 [522338]
Company
Phenomix Corp
Structure
Download
2D MOL

3D MOL
Canonical SMILES
N1C[C@@H](CC1)NCC(=O)N1[C@@H](CCC1)B(O)O
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Inhibitor [530838]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 522338ClinicalTrials.gov (NCT00690638) Safety and Efficacy Study of Dutogliptin/PHX1149T to Treat Type 2 Diabetes Mellitus. U.S. National Institutes of Health.
Ref 530838Dutogliptin, a selective DPP4 inhibitor, improves glycaemic control in patients with type 2 diabetes: a 12-week, double-blind, randomized, placebo-controlled, multicentre trial. Diabetes Obes Metab. 2010 Apr;12(4):348-55.

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