TTD | Drug: D04YLU

Drug General Information
Drug ID	D04YLU
Former ID	DIB008025
Drug Name	AZ-599
Synonyms	CB1 agonist (pain), AstraZeneca
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Investigative	[543877]
Company	AstraZeneca plc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	O=S(=O)(n1c2ccc(C(=O)N3CCC(CC3)C)cc2c2c1CCN(C1CCOCC1)C2<br />)CC
Target and Pathway
Target(s)	Cannabinoid receptor 1	Target Info	Agonist	[543877]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
PANTHER Pathway	Endogenous cannabinoid signaling
Pathway Interaction Database	N-cadherin signaling events
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	BDNF signaling pathway
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 543877	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 56).
Ref 543877	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 56).

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Drug Information