TTD | Drug: D05AEE

Drug General Information
Drug ID	D05AEE
Former ID	DIB003973
Drug Name	RG7935
Drug Type	Antibody
Indication	Parkinson's disease [ICD9: 332; ICD10:G20]		Phase 1	[549547]
Target and Pathway
Target(s)	Alpha-synuclein	Target Info		[544219], [550986]
KEGG Pathway	Alzheimer's disease
KEGG Pathway	Parkinson's disease
NetPath Pathway	Leptin Signaling Pathway
NetPath Pathway	RANKL Signaling Pathway
PANTHER Pathway	Parkinson disease
Pathway Interaction Database	Alpha-synuclein signaling
Reactome	Amyloid formation
WikiPathways	Ectoderm Differentiation
	Parkinsons Disease Pathway
	Parkin-Ubiquitin Proteasomal System pathway
	Alzheimers Disease
References
Ref 549547	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040327)
Ref 544219	alpha-Synuclein in Parkinson's Disease. Cold Spring Harb Perspect Med. 2012 February; 2(2): a009399.
Ref 550986	The Anticholinesterase Phenserine and Its Enantiomer Posiphen as 5??ntranslated-Region-Directed Translation Blockers of the Parkinson's Alpha Synuclein Expression. Parkinson's Disease Volume 2012 (2012), Article ID 142372, Page(13).

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Drug Information