Drug General Information
Drug ID
D05BYO
Former ID
DCL001203
Drug Name
ISIS-SOD1
Drug Type
Antisense drug
Indication Amyotrophic lateral sclerosis [ICD9: 335.2; ICD10:G12.2] Phase 1 [551052]
Company
ISIS Pharm
Target and Pathway
Target(s) mRNA of copper zinc superoxide dismutase 1 Target Info [551052]
BioCyc Pathway Reactive oxygen species degradation
KEGG Pathway Peroxisome
Amyotrophic lateral sclerosis (ALS)
Huntington's disease
Prion diseases
NetPath Pathway TCR Signaling Pathway
Pathway Interaction Database Validated nuclear estrogen receptor alpha network
FOXA1 transcription factor network
PathWhiz Pathway Degradation of Superoxides
Reactome Platelet degranulation
Detoxification of Reactive Oxygen Species
WikiPathways Oxidative Stress
Copper homeostasis
Detoxification of Reactive Oxygen Species
Nifedipine Activity
Amyotrophic lateral sclerosis (ALS)
Dopamine metabolism
AGE/RAGE pathway
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.