Drug General Information
Drug ID
D05CRG
Former ID
DNC000842
Drug Name
L-054852
Drug Type
Small molecular drug
Indication Acromegaly [ICD9: 253; ICD10:E22.0] Investigative [536151]
Company
Merck
Structure
Download
2D MOL

3D MOL

Formula
C32H43N5O2S
Canonical SMILES
CC(C)C(NC(=O)C(C(C)C1=CNC2=CC=CC=C21)NC(=O)N3CCC4(CCC5=<br />CC=CC=C54)CC3)SCCN
InChI
1S/C32H43N5O2S/c1-21(2)30(40-19-16-33)36-29(38)28(22(3)25-20-34-27-11-7-5-9-24(25)27)35-31(39)37-17-14-32(15-18-37)13-12-23-8-4-6-10-26(23)32/h4-11,20-22,28,30,34H,12-19,33H2,1-3H3,(H,35,39)(H,36,38)
InChIKey
UDRSIUYQZOTMRD-UHFFFAOYSA-N
CAS Number
CAS 214471-63-3
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Somatostatin receptor type 2 Target Info Agonist [536151]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways SIDS Susceptibility Pathways
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 536151Treatment strategies for acromegaly. Expert Opin Emerg Drugs. 2005 Nov;10(4):875-90.
Ref 536151Treatment strategies for acromegaly. Expert Opin Emerg Drugs. 2005 Nov;10(4):875-90.

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