Drug General Information
Drug ID
D05DCL
Former ID
DIB006615
Drug Name
ZYT-1
Synonyms
Lipid lowering molecule (dyslipidemia), Zydus-Cadila
Indication Lipid metabolism disorder [ICD10:E75-E78] Phase 1 [523811]
Company
Zydus-Cadila Group
Target and Pathway
Target(s) Thyroid hormone receptor beta-1 Target Info Modulator [1572591]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear Receptors
References
Ref 523811ClinicalTrials.gov (NCT01543269) A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers. U.S. National Institutes of Health.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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