Drug Information

Drug General Information
Drug ID
D05EGR
Former ID
DNC002848
Drug Name
Bis-Napthyl Beta-Ketophosphonic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C22H17O4P
Canonical SMILES
C1=CC=C2C=C(C=CC2=C1)C(=O)C(C3=CC=CC4=CC=CC=C43)P(=O)(O<br />)O
InChI
1S/C22H17O4P/c23-21(18-13-12-15-6-1-2-8-17(15)14-18)22(27(24,25)26)20-11-5-9-16-7-3-4-10-19(16)20/h1-14,22H,(H2,24,25,26)/t22-/m1/s1
InChIKey
OFHMUASCSJJNNA-JOCHJYFZSA-N
PubChem Compound ID
446833
PubChem Substance ID
7888571, 36889148, 46392394, 46508345, 49661377, 53021508, 104637092, 160965555
Target and Pathway
Target(s) Cathepsin G Target Info Inhibitor [551393]
KEGG Pathway Neuroactive ligand-receptor interaction
Lysosome
Renin-angiotensin system
Amoebiasis
Systemic lupus erythematosus
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
WikiPathways ACE Inhibitor Pathway
Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.