Drug Information

Drug General Information
Drug ID
D05GGN
Former ID
DIB006079
Drug Name
Heparin
Synonyms
Heparin (buccal)
Drug Type
Small molecular drug
Indication Deep vein thrombosis [ICD9: 437.6, 453, 453.40, 671.5, 671.9; ICD10:I80-I82, I80.2] Approved [467549]
Company
Generex Biotechnology Corp
Formula
C26H41NO34S4
InChI
InChI=1S/C26H41NO34S4/c1-4(28)27-7-9(30)8(29)6(2-52-63(43,44)45)53-24(7)56-15-10(31)11(32)25(58-19(15)21(36)37)55-13-5(3-62(40,41)42)14(60-64(46,47)48)26(59-22(13)38)57-16-12(33)17(61-65(49,50)51)23(39)54-18(16)20(34)35/h5-19,22-26,29-33,38-39H,2-3H2,1H3,(H,27,28)(H,34,35)(H,36,37)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)/t5-,6+,7+,8+,9+,10+,11+,12-,13-,14+,15-,16-,17+,18+,19-,22-,23?,24+,25+,26-/m0/s1
InChIKey
ZFGMDIBRIDKWMY-PASTXAENSA-N
PubChem Compound ID
22833565
PubChem Substance ID
40649282, 53790558, 103654804, 126524021, 135297230, 137237550, 178101031, 225067056
Target and Pathway
Target(s) Antithrombin-III Target Info Modulator [543670]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
Pathway Interaction Database Glypican 1 network
Reactome Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
WikiPathways Complement and Coagulation Cascades
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 467549(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4214).
Ref 543670(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2632).

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