Drug General Information
Drug ID	D05IHR
Former ID	DNC012812
Drug Name	9-Phenyl-2,3-dihydro-1H-indeno[2,1-c]pyridine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[525803]
Structure		Download 2D MOL 3D MOL
Formula	C18H15N
Canonical SMILES	C1C=C2C(=C(C3=CC=CC=C23)C4=CC=CC=C4)CN1
InChI	1S/C18H15N/c1-2-6-13(7-3-1)18-16-9-5-4-8-14(16)15-10-11-19-12-17(15)18/h1-10,19H,11-12H2
InChIKey	KIUIXTNMEMKNGK-UHFFFAOYSA-N
PubChem Compound ID	15830914
Target and Pathway
Target(s)	Histamine H1 receptor	Target Info	Inhibitor	[525803]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	Histamine H1 receptor mediated signaling pathway
Reactome	Histamine receptors
	G alpha (q) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	IL-4 Signaling Pathway
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 525803	Bioorg Med Chem Lett. 2000 Jun 5;10(11):1277-9.Conformationally-restricted ligands for the histamine H1 receptor.
Ref 525803	Bioorg Med Chem Lett. 2000 Jun 5;10(11):1277-9.Conformationally-restricted ligands for the histamine H1 receptor.

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