Drug Information

Drug General Information
Drug ID
D05ILZ
Former ID
DNCL001666
Drug Name
NN8209
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Discontinued in Phase 2 [548112]
Company
Novo Nordisk
Target and Pathway
Target(s) C5aR Target Info Modulator [532298]
KEGG Pathway Neuroactive ligand-receptor interaction
Complement and coagulation cascades
Staphylococcus aureus infection
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways Complement and Coagulation Cascades
Human Complement System
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 548112Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022053)
Ref 532298Complement in immune and inflammatory disorders: therapeutic interventions. J Immunol. 2013 Apr 15;190(8):3839-47.

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