Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05KRC
|
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| Former ID |
DIB009815
|
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| Drug Name |
Emopamil
|
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| Synonyms |
Levemopamil
|
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| Drug Type |
Small molecular drug
|
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| Indication | Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] | Terminated | [1] | ||
| Company |
Knoll GmbH
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C23H30N2
|
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| Canonical SMILES |
C(C#N)(c1ccccc1)(C(C)C)CCCN(CCc1ccccc1)C
|
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| CAS Number |
CAS 78370-13-5
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Calcium channel | Target Info | Modulator | [1] | |
| 5-HT 2 receptor | Target Info | Modulator | [1] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| References | |||||
| REF 1 | Calcium entry and 5-HT2 receptor blockade in oliguric ischaemic acute renal failure: effects of levemopamil in conscious rats. Br J Pharmacol. 1996 Mar;117(6):1348-54. | ||||
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