Drug Information
Drug General Information | |||||
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Drug ID |
D05KRC
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Former ID |
DIB009815
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Drug Name |
Emopamil
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Synonyms |
Levemopamil
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Drug Type |
Small molecular drug
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Indication | Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] | Terminated | [1] | ||
Company |
Knoll GmbH
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Structure |
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Download2D MOL |
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Formula |
C23H30N2
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Canonical SMILES |
C(C#N)(c1ccccc1)(C(C)C)CCCN(CCc1ccccc1)C
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CAS Number |
CAS 78370-13-5
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Calcium channel | Target Info | Modulator | [1] | |
5-HT 2 receptor | Target Info | Modulator | [1] | ||
KEGG Pathway | Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Gap junction | |||||
Serotonergic synapse | |||||
Inflammatory mediator regulation of TRP channels | |||||
References | |||||
REF 1 | Calcium entry and 5-HT2 receptor blockade in oliguric ischaemic acute renal failure: effects of levemopamil in conscious rats. Br J Pharmacol. 1996 Mar;117(6):1348-54. | ||||
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