Drug Information

Drug General Information
Drug ID
D05KVN
Former ID
DNC012217
Drug Name
2-(8-Imidazol-1-yl-octyl)-isoindole-1,3-dione
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533459]
Structure
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2D MOL

3D MOL
Formula
C19H23N3O2
Canonical SMILES
C1=CC=C2C(=C1)C(=O)N(C2=O)CCCCCCCCN3C=CN=C3
InChI
1S/C19H23N3O2/c23-18-16-9-5-6-10-17(16)19(24)22(18)13-8-4-2-1-3-7-12-21-14-11-20-15-21/h5-6,9-11,14-15H,1-4,7-8,12-13H2
InChIKey
UYNFUMGZMJRXFD-UHFFFAOYSA-N
PubChem Compound ID
13580028
Target and Pathway
Target(s) Thromboxane-A synthase Target Info Inhibitor [533459]
BioCyc Pathway C20 prostanoid biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Platelet activation
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Prostaglandin Synthesis and Regulation
Arachidonic acid metabolism
Phase 1 - Functionalization of compounds
Eicosanoid Synthesis
References
Ref 533459J Med Chem. 1986 May;29(5):816-9.Thromboxane synthetase inhibitors and antihypertensive agents. 2. N-[(1H-imidazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones and N-[(1H-1,2,4-triazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones as unique antihypertensive agents.
Ref 533459J Med Chem. 1986 May;29(5):816-9.Thromboxane synthetase inhibitors and antihypertensive agents. 2. N-[(1H-imidazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones and N-[(1H-1,2,4-triazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones as unique antihypertensive agents.

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