Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05NTY
|
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| Former ID |
DIB011453
|
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| Drug Name |
NPC-18166
|
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| Synonyms |
IDDB8389
|
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| Indication | Psychotic disorders [ICD9: 290-299; ICD10:F20-F29] | Terminated | [1] | ||
| Company |
Scios Inc
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
c12c([nH]c3c1cc(cc3)F)C1CN(C2CC1)CCCC(=O)c1ccc(cc1)F
|
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| Target and Pathway | |||||
| Target(s) | 5-HT 2 receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004563) | ||||
| REF 2 | WO patent application no. 2004,0825,84, 5ht2c receptor antagonists in the treatment of schizophrenia. | ||||
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