Drug Information
Drug General Information | |||||
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Drug ID |
D05PZA
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Former ID |
DNC009023
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Drug Name |
N-benzylacetimidamide hydrobromide
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C9H13BrN2
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Canonical SMILES |
CC(=NCC1=CC=CC=C1)N.Br
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InChI |
1S/C9H12N2.BrH/c1-8(10)11-7-9-5-3-2-4-6-9;/h2-6H,7H2,1H3,(H2,10,11);1H
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InChIKey |
RUQJDXJQOUUQHG-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Nitric oxide synthase, inducible | Target Info | Inhibitor | [1] | |
BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
KEGG Pathway | Arginine biosynthesis | ||||
Arginine and proline metabolism | |||||
Metabolic pathways | |||||
Calcium signaling pathway | |||||
HIF-1 signaling pathway | |||||
Peroxisome | |||||
Salmonella infection | |||||
Pertussis | |||||
Leishmaniasis | |||||
Chagas disease (American trypanosomiasis) | |||||
Toxoplasmosis | |||||
Amoebiasis | |||||
Tuberculosis | |||||
Pathways in cancer | |||||
Small cell lung cancer | |||||
NetPath Pathway | IL1 Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
Pathway Interaction Database | IL12-mediated signaling events | ||||
Alpha9 beta1 integrin signaling events | |||||
ATF-2 transcription factor network | |||||
IL23-mediated signaling events | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
HIF-1-alpha transcription factor network | |||||
Reactome | ROS production in response to bacteria | ||||
Nitric oxide stimulates guanylate cyclase | |||||
WikiPathways | Type II interferon signaling (IFNG) | ||||
Spinal Cord Injury | |||||
AGE/RAGE pathway | |||||
Effects of Nitric Oxide | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2010 Nov 15;20(22):6495-9. Epub 2010 Sep 17.N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase. | ||||
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