Drug Information

Drug General Information
Drug ID
D05QBF
Former ID
DNC002339
Drug Name
Devazepide
Drug Type
Small molecular drug
Indication Gastrointestinal disease [ICD10:K00-K93] Investigative [543268]
Structure
Download
2D MOL

3D MOL
Formula
C25H20N4O2
InChI
InChI=1S/C25H20N4O2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26H,1H3,(H,28,30)
InChIKey
NFHRQQKPEBFUJK-UHFFFAOYSA-N
CAS Number
CAS 103420-77-5
PubChem Compound ID
59751
PubChem Substance ID
6613367, 8186492, 14781731, 43117251, 47285862, 47510063, 49982465, 49983520, 50794156, 57313967, 85209940, 104318983, 117565957, 126422049, 128694066, 135017793, 135650466, 136930114, 162356071, 163139605, 178100467, 179293988, 225145694, 230768744
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Antagonist [536549]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543268(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 878).
Ref 536549Privileged structures: a useful concept for the rational design of new lead drug candidates. Mini Rev Med Chem. 2007 Nov;7(11):1108-19.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.