Drug General Information
Drug ID
D05RZE
Former ID
DIB003702
Drug Name
LY-2623091
Synonyms
Chronic renal disease therapy, Eli Lilly
Indication Chronic kidney disease [ICD9: 403, 585.1-585.5, 585.9; ICD10:N18] Phase 2 [524840]
Company
Eli Lilly & Co
Structure
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2D MOL

3D MOL

Target and Pathway
Target(s) Mineralocorticoid receptor Target Info Antagonist [533270]
KEGG Pathway Aldosterone-regulated sodium reabsorption
PathWhiz Pathway Kidney Function
WikiPathways ACE Inhibitor Pathway
References
Ref 524840ClinicalTrials.gov (NCT02194465) A Study of LY2623091 in Participants With High Blood Pressure. U.S. National Institutes of Health.
Ref 533270Nonsteroidal antagonists of the mineralocorticoid receptor. Curr Opin Nephrol Hypertens. 2015 Sep;24(5):417-24.

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