Drug Information

Drug General Information
Drug ID
D05SHQ
Former ID
DIB002586
Drug Name
ASP-2002
Synonyms
Integrin antagonist (ulcerative colitis), Asphelia
Indication Ulcerative colitis [ICD9: 556; ICD10:K51] Investigative [550392]
Company
Asphelia Pharmaceuticals Inc
Target and Pathway
Target(s) Integrin alpha-4 Target Info Antagonist [550392]
KEGG Pathway PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Hematopoietic cell lineage
Leukocyte transendothelial migration
Intestinal immune network for IgA production
Regulation of actin cytoskeleton
Leishmaniasis
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
PANTHER Pathway Integrin signalling pathway
Pathway Interaction Database Beta1 integrin cell surface interactions
Integrin family cell surface interactions
Arf6 trafficking events
CXCR4-mediated signaling events
Plexin-D1 Signaling
a4b7 Integrin signaling
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
VEGFR3 signaling in lymphatic endothelium
Alpha4 beta1 integrin signaling events
Reactome Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Integrin cell surface interactions
WikiPathways Focal Adhesion
Arrhythmogenic Right Ventricular Cardiomyopathy
Integrin-mediated Cell Adhesion
Integrin cell surface interactions
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
References
Ref 550392Asphelia to Present at C21 BioVentures Conference in Napa, CA. 10th Annual C21 BioVentures. May 15, 2008.
Ref 550392Asphelia to Present at C21 BioVentures Conference in Napa, CA. 10th Annual C21 BioVentures. May 15, 2008.

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