Drug General Information
Drug ID	D05SNS
Former ID	DNC003610
Drug Name	2-(2-Hydroxycarbamoyl-ethyl)-pentanedioic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526637]
Structure		Download 2D MOL 3D MOL
Formula	C8H13NO6
Canonical SMILES	C(CC(=O)NO)C(CCC(=O)O)C(=O)O
InChI	1S/C8H13NO6/c10-6(9-15)3-1-5(8(13)14)2-4-7(11)12/h5,15H,1-4H2,(H,9,10)(H,11,12)(H,13,14)
InChIKey	HTZIUDNKEYUDDE-UHFFFAOYSA-N
PubChem Compound ID	20778197
Target and Pathway
Target(s)	Glutamate carboxypeptidase II	Target Info	Inhibitor	[526637]
KEGG Pathway	Alanine, aspartate and glutamate metabolism
	Metabolic pathways
	Vitamin digestion and absorption
NetPath Pathway	TCR Signaling Pathway
	TNFalpha Signaling Pathway
Reactome	Amino acid synthesis and interconversion (transamination)
WikiPathways	One Carbon Metabolism
References
Ref 526637	Bioorg Med Chem Lett. 2003 Jul 7;13(13):2097-100.Synthesis and biological evaluation of hydroxamate-Based inhibitors of glutamate carboxypeptidase II.
Ref 526637	Bioorg Med Chem Lett. 2003 Jul 7;13(13):2097-100.Synthesis and biological evaluation of hydroxamate-Based inhibitors of glutamate carboxypeptidase II.

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