Drug General Information
Drug ID
D05SYY
Former ID
DNC003818
Drug Name
7-Bromo-2-phenyl-[1,8]naphthyridin-4-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527090]
Structure
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2D MOL

3D MOL

Formula
C14H9BrN2O
Canonical SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)N=C(C=C3)Br
InChI
1S/C14H9BrN2O/c15-13-7-6-10-12(18)8-11(16-14(10)17-13)9-4-2-1-3-5-9/h1-8H,(H,16,17,18)
InChIKey
ZVIMMGQTBAKKGA-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [527090]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 527090J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.
Ref 527090J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.

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