Drug Information
Drug General Information | |||||
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Drug ID |
D05SZG
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Former ID |
DIB020801
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Drug Name |
resolvin D1
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540557] | ||
Formula |
C22H32O5
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InChI |
InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21-/m0/s1
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InChIKey |
OIWTWACQMDFHJG-LDOXQWQISA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Transient receptor potential cation channel subfamily A member 1 | Target Info | Inhibitor (gating inhibitor) | [531183] | |
FMLP-related receptor I | Target Info | Agonist | [530641] | ||
GPR32 | Target Info | Agonist | [530641] | ||
KEGG Pathway | Inflammatory mediator regulation of TRP channels | ||||
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | ||||
References | |||||
Ref 530641 | Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1660-5. | ||||
Ref 531183 | Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception. Br J Pharmacol. 2010 Oct;161(3):707-20. |
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