Drug Information

Drug General Information
Drug ID
D05TKO
Former ID
DIB010271
Drug Name
Retagliptin
Synonyms
DPP4 inhibitors, Shanghai Hengrui Pharmaceutical Co Ltd; SHR-1039; SHR-1040; DPPIV inhibitors (diabetes), Shanghai Hengrui Pharmaceutical Co Ltd; Dipeptidyl peptidase IV inhibitors (diabetes), Shanghai Hengrui Pharmaceutical Co Ltd
Indication Non-insulin dependent diabetes [ICD10:E11.9] Investigative [543447]
Company
Shanghai Hengrui Pharmaceutical Co Ltd
Structure
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2D MOL

3D MOL
Canonical SMILES
C1N(CC2C1CNC(=O)C2)C(=O)CC(Cc1c(cc(c(c1)F)F)F)N
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Inhibitor [543447]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 543447(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612).
Ref 543447(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612).

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