Drug Information

Drug General Information
Drug ID
D05WKT
Former ID
DIB016706
Drug Name
PK-44
Synonyms
PK-44; DPP-IV inhibitors (diabetes); DPP-IV inhibitors (diabetes), PeakDale
Indication Non-insulin dependent diabetes [ICD10:E11.9] Investigative [543447]
Company
Peakdale Molecular
Structure
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2D MOL

3D MOL
Canonical SMILES
FC(F)(c1n2CCN(C(=O)C[C@@H](Cc3n[nH]c4c3ccc(c4F)F)N)Cc2n<br />n1)F
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Inhibitor [543447]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 543447(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612).
Ref 543447(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612).

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