Drug Information

Drug General Information
Drug ID
D05WQT
Former ID
DIB008520
Drug Name
Flanvotumab
Synonyms
IMC-20D7S; Gp75 monoclonal antibodies (melanoma), ImClone; Gp75 mAb (melanoma), ImClone/Eli Lilly; GP75/TRP1 mAbs (melanoma), ImClone/Eli Lilly
Drug Type
Antibody
Indication Melanoma [ICD9: 172; ICD10:C43] Phase 1 [523062]
Company
Eli lilly
CAS Number
CAS 1188277-05-5
Target and Pathway
Target(s) DHICA oxidase Target Info [550460]
BioCyc Pathway Eumelanin biosynthesis
KEGG Pathway Tyrosine metabolism
Metabolic pathways
Melanogenesis
Pathway Interaction Database Direct p53 effectors
PathWhiz Pathway Degradation of Superoxides
References
Ref 523062ClinicalTrials.gov (NCT01137006) An Open-Label, Dose-Escalation Study of IMC-20D7S In Patients With Malignant Melanoma. U.S. National Institutes of Health.
Ref 550460National Cancer Institute Drug Dictionary (drug id 675217).

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