Drug Information

Drug General Information
Drug ID
D05XUY
Former ID
DNC000827
Drug Name
JM216
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [525639]
Structure
Download
2D MOL

3D MOL
Formula
C10H24Cl2N2O4Pt
Canonical SMILES
CC(=O)O.CC(=O)O.C1CCC(CC1)N.N.Cl[Pt]Cl
InChI
1S/C6H13N.2C2H4O2.2ClH.H3N.Pt/c7-6-4-2-1-3-5-6;2*1-2(3)4;;;;/h6H,1-5,7H2;2*1H3,(H,3,4);2*1H;1H3;/q;;;;;;+2/p-2
InChIKey
TWEQNPPRXJRHHM-UHFFFAOYSA-L
CAS Number
CAS 12126-59-9
PubChem Compound ID
6918220
PubChem Substance ID
12014708, 14810909, 43529608, 47207468, 50271886, 125536506, 126648524, 135374014, 152053656, 164786730, 249582592, 252390159, 252480823
Target and Pathway
Target(s) Human DNA Target Info Modulator [1572591]
References
Ref 525639Phase II study of oral platinum drug JM216 as first-line treatment in patients with small-cell lung cancer. J Clin Oncol. 1999 Dec;17(12):3822-7.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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