Drug Information

Drug General Information
Drug ID
D05XXF
Former ID
DIB011709
Drug Name
ORMD-0901
Synonyms
Exenatide-4 (oral, diabetes), Oramed; GLP1-analog (oral, non-insulin dependent diabetes), Oramed Pharmaceuticals
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [548795]
Company
Oramed Pharmaceuticals Inc
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Agonist [531282]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 548795Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028920)
Ref 531282Novel glucagon-like peptide-1 analog delivered orally reduces postprandial glucose excursions in porcine and canine models. J Diabetes Sci Technol. 2010 Nov 1;4(6):1516-23.

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