TTD | Drug: D05YZC

Drug General Information
Drug ID	D05YZC
Former ID	DIB018272
Drug Name	[3H]devazepide
Synonyms	[3H]-devazepide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540415]
Structure		Download 2D MOL 3D MOL
Formula	C25H20N4O2
InChI	InChI=1S/C25H20N4O2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26H,1H3,(H,28,30)
InChIKey	NFHRQQKPEBFUJK-UHFFFAOYSA-N
PubChem Compound ID	59751
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Antagonist	[533408]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540415	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3476).
Ref 533408	Characterization of the binding of [3H]-(+/-)-L-364,718: a new potent, nonpeptide cholecystokinin antagonist radioligand selective for peripheral receptors. Mol Pharmacol. 1986 Sep;30(3):212-7.

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Drug Information