Drug Information

Drug General Information
Drug ID
D06ACR
Former ID
DIB019405
Drug Name
compound 29a
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531413], [541076]
Formula
C22H26N4O6S
InChI
InChI=1S/C22H26N4O6S/c1-22(2,3)31-21(27)26-11-9-15(10-12-26)30-20-19-18(23-13-24-20)17(25-32-19)14-5-7-16(8-6-14)33(4,28)29/h5-8,13,15H,9-12H2,1-4H3
InChIKey
JYRWUSXRTGACLY-UHFFFAOYSA-N
PubChem Compound ID
11397354
PubChem Substance ID
16492226, 23547825, 42476515, 75448564, 127343511, 127343512, 127343513, 131272255, 131346381, 137219198, 139392298, 178102367, 198961157, 223370116, 223931748, 226716485, 248916646
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531413]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Ref 541076(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5741).
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

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