Drug General Information
Drug ID	D06CED
Former ID	DNC010812
Drug Name	3'-(5-Chloro-2-thienyl)biphenyl-3-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530868]
Structure		Download 2D MOL 3D MOL
Formula	C16H11ClOS
Canonical SMILES	C1=CC(=CC(=C1)C2=CC=C(S2)Cl)C3=CC(=CC=C3)O
InChI	1S/C16H11ClOS/c17-16-8-7-15(19-16)13-5-1-3-11(9-13)12-4-2-6-14(18)10-12/h1-10,18H
InChIKey	IBTNRYGKAUWUJS-UHFFFAOYSA-N
PubChem Compound ID	46844318
Target and Pathway
Target(s)	Estradiol 17 beta-dehydrogenase 1	Target Info	Inhibitor	[530868]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	The canonical retinoid cycle in rods (twilight vision)
WikiPathways	Steroid Biosynthesis
	Metabolism of steroid hormones and vitamin D
	Prostate Cancer
References
Ref 530868	Bioorg Med Chem. 2010 May 15;18(10):3494-505. Epub 2010 Mar 29.Novel estrone mimetics with high 17beta-HSD1 inhibitory activity.
Ref 530868	Bioorg Med Chem. 2010 May 15;18(10):3494-505. Epub 2010 Mar 29.Novel estrone mimetics with high 17beta-HSD1 inhibitory activity.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.