Drug Information

Drug General Information
Drug ID
D06FIF
Former ID
DNC013525
Drug Name
CP-376395
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540434]
Structure
Download
2D MOL

3D MOL
Formula
C21H30N2O
InChI
InChI=1S/C21H30N2O/c1-8-18(9-2)23-19-12-16(6)22-21(17(19)7)24-20-14(4)10-13(3)11-15(20)5/h10-12,18H,8-9H2,1-7H3,(H,22,23)
InChIKey
VIZBSVDBNLAVAW-UHFFFAOYSA-N
PubChem Compound ID
9862166
PubChem Substance ID
14826464, 24154936, 45284444, 49689040, 78737523, 93815006, 103578387, 125434269, 129481966, 134350730, 142534105, 152134004, 163686882, 163893992, 172649528, 178100484, 187072011, 198964012, 208013722, 223924829, 226494515, 243849291, 251963039
Target and Pathway
Target(s) Corticotropin releasing factor receptor 1 Target Info Inhibitor [529324]
KEGG Pathway Neuroactive ligand-receptor interaction
Long-term depression
NetPath Pathway TNFalpha Signaling Pathway
PANTHER Pathway Cortocotropin releasing factor receptor signaling pathway
Reactome Class B/2 (Secretin family receptors)
G alpha (s) signalling events
WikiPathways GPCRs, Class B Secretin-like
Myometrial Relaxation and Contraction Pathways
Corticotropin-releasing hormone
GPCR ligand binding
GPCR downstream signaling
References
Ref 540434(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3496).
Ref 529324J Med Chem. 2008 Mar 13;51(5):1385-92. Epub 2008 Feb 21.2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.