TTD | Drug: D06FWM

Drug General Information
Drug ID	D06FWM
Former ID	DNC007816
Drug Name	N-(3-(1H-indol-4-yloxy)propyl)cyclohexanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529018]
Structure		Download 2D MOL 3D MOL
Formula	C17H24N2O
Canonical SMILES	C1CCC(CC1)NCCCOC2=CC=CC3=C2C=CN3
InChI	1S/C17H24N2O/c1-2-6-14(7-3-1)18-11-5-13-20-17-9-4-8-16-15(17)10-12-19-16/h4,8-10,12,14,18-19H,1-3,5-7,11,13H2
InChIKey	QVATUGJQJMJAPA-UHFFFAOYSA-N
PubChem Compound ID	44433247
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Inhibitor	[529018]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529018	Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.
Ref 529018	Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

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Drug Information