Drug Information

Drug General Information
Drug ID
D06FWY
Former ID
DNC006875
Drug Name
KYS-05070
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528345]
Structure
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2D MOL

3D MOL
Formula
C28H33N5O3S
Canonical SMILES
CCN1C(C2=CC=CC=C2N=C1N(C)C)CC(=O)NCC3=CC=C(C=C3)NS(=O)(<br />=O)C4=CC=C(C=C4)C
InChI
1S/C28H33N5O3S/c1-5-33-26(24-8-6-7-9-25(24)30-28(33)32(3)4)18-27(34)29-19-21-12-14-22(15-13-21)31-37(35,36)23-16-10-20(2)11-17-23/h6-17,26,31H,5,18-19H2,1-4H3,(H,29,34)
InChIKey
UBFZYFFOQNFRPD-UHFFFAOYSA-N
PubChem Compound ID
44416787
Target and Pathway
Target(s) Voltage-dependent T-type calcium channel alpha-1G subunit Target Info Inhibitor [528345]
KEGG Pathway MAPK signaling pathway
Calcium signaling pathway
Circadian entrainment
Type II diabetes mellitus
PANTHER Pathway Endogenous cannabinoid signaling
GABA-B receptor II signaling
Nicotine pharmacodynamics pathway
Pathway Interaction Database Regulation of nuclear beta catenin signaling and target gene transcription
PathWhiz Pathway Muscle/Heart Contraction
Reactome NCAM1 interactions
WikiPathways NCAM signaling for neurite out-growth
Nicotine Activity on Chromaffin Cells
References
Ref 528345Bioorg Med Chem Lett. 2006 Oct 1;16(19):5014-7. Epub 2006 Jul 28.Growth inhibition of human cancer cells in vitro by T-type calcium channel blockers.
Ref 528345Bioorg Med Chem Lett. 2006 Oct 1;16(19):5014-7. Epub 2006 Jul 28.Growth inhibition of human cancer cells in vitro by T-type calcium channel blockers.

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