TTD | Drug: D06HXC

Drug General Information
Drug ID	D06HXC
Former ID	DNC001043
Drug Name	NPY-1 antagonist
Drug Type	Small molecular drug
Indication	Eating disorders reduction in food intake obesity anxiety [ICD9: 307.5; ICD10:F50]		Investigative	[552024]
Company	Pfizer
Structure		Download 2D MOL 3D MOL
Formula	C30H35N5O3
Canonical SMILES	C1CC(OC1)CNC(=O)NC(=NCC2=CC(=CC=C2)CNC(=O)C(CC3=CC=CC=C<br />3)C4=CC=CC=C4)N
InChI	1S/C30H35N5O3/c31-29(35-30(37)34-21-26-15-8-16-38-26)33-20-24-12-7-11-23(17-24)19-32-28(36)27(25-13-5-2-6-14-25)18-22-9-3-1-4-10-22/h1-7,9-14,17,26-27H,8,15-16,18-21H2,(H,32,36)(H4,31,33,34,35,37)
InChIKey	BSGMHDGHMYUSDC-UHFFFAOYSA-N
CAS Number	CAS 262418-00-8
PubChem Compound ID	20725582
PubChem Substance ID	34029431, 134340300, 142590817, 248636393
Target and Pathway
Target(s)	Neuropeptide Y receptor type 1	Target Info	Antagonist	[536225]
KEGG Pathway	cAMP signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	FSH Signaling Pathway
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	Endothelin Pathways
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 552024	Neuropeptide Y receptor antagonists. IDrugs. 2001 Aug;4(8):920-7.
Ref 536225	Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36.

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Drug Information