Drug Information

Drug General Information
Drug ID
D06IEX
Former ID
DIB006931
Drug Name
Cardiotrophin-1
Synonyms
Cardiotrophin-1 (acute liver failure/obesity/interferon stimulator)
Indication Acute liver failure [ICD10:K72] Phase 1 [468092], [523426]
Company
Digna Biotech SL
Target and Pathway
Target(s) Cardiotrophin-1 Target Info Stimulator [1572591]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
WikiPathways MicroRNAs in cardiomyocyte hypertrophy
Physiological and Pathological Hypertrophy of the Heart
References
Ref 468092(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4906).
Ref 523426ClinicalTrials.gov (NCT01334697) Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of Cardiotrophin-1 in Healthy Volunteers. U.S. National Institutes of Health.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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