Drug Information

Drug General Information
Drug ID
D06JBV
Former ID
DIB005450
Drug Name
SGN LIV1A
Drug Type
Antibody
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Phase 1 [524488]
Company
Seattle genetics
Target and Pathway
Target(s) Zinc transporter ZIP6 Target Info [532973]
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
References
Ref 524488ClinicalTrials.gov (NCT01969643) A Safety Study of SGN-LIV1A in Breast Cancer Patients. U.S. National Institutes of Health.
Ref 532973SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer. Mol Cancer Ther. 2014 Dec;13(12):2991-3000.

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