Drug Information
Drug General Information | |||||
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Drug ID |
D06LQH
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Former ID |
DIB020569
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Drug Name |
N-propylnorapomorphine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C19H21NO2
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InChI |
InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3
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InChIKey |
BTGAJCKRXPNBFI-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | D(1B) dopamine receptor | Target Info | Agonist | [2] | |
Dopamine D1 receptor | Target Info | Agonist | [2] | ||
KEGG Pathway | Calcium signaling pathway | ||||
cAMP signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Dopaminergic synapsehsa04020:Calcium signaling pathway | |||||
Gap junction | |||||
Dopaminergic synapse | |||||
Parkinson's disease | |||||
Cocaine addiction | |||||
Amphetamine addiction | |||||
Morphine addiction | |||||
Alcoholism | |||||
PANTHER Pathway | Dopamine receptor mediated signaling pathwayP05912:Dopamine receptor mediated signaling pathway | ||||
PathWhiz Pathway | Dopamine Activation of Neurological Reward System | ||||
Reactome | Dopamine receptors | ||||
G alpha (s) signalling eventsR-HSA-390651:Dopamine receptors | |||||
G alpha (s) signalling events | |||||
WikiPathways | Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP666:Hypothetical Network for Drug Addiction | |||||
Genes and (Common) Pathways Underlying Drug Addiction | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 934). | ||||
REF 2 | Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature. 1991 Apr 18;350(6319):614-9. | ||||
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